A Transformative Journey as a CASL-CLF Clinical Fellow at King’s College Hospital – By Alex Frolkis

CASL-CLF Final Report

Overview

When I applied for the CASL-CLF clinical fellowship funding, I outlined my goal of becoming a well-rounded transplant hepatologist, with a focus on gaining clinical experience at King’s College Hospital (KCH) to enhance my ability to provide exceptional care in Canada. My year at KCH exceeded my expectations, offering a dynamic combination of clinical, research, and educational opportunities. I am grateful I could be a CASL-CLF fellow.

Clinical Experiences
My goal in going to KCH was to gain clinical experience. This goal was achieved in the following ways:

I acted as consultant for general hepatology for one week.

I lead transplant ward rounds with consultant support at the daily hand over meetings.

Participate in transplant assessments, including presenting and advocating for patients at the transplant listing meetings.

Though I was not included in the set rota, I sought out clinic opportunities. I worked in a variety of specialized clinics, which provided exposure to a broad spectrum of hepatology subspecialties including:

  • Autoimmune Liver Disease
  • Transplant Waiting List Management
  • Post-Transplant Care
  • Obstetric Liver Medicine
  • Viral Hepatitis
  • Young Adult Transition
  • Hepatocellular Carcinoma
  • Alcohol-Related Liver Disease

These experiences have been instrumental in strengthening my clinical expertise and preparing me to manage complex hepatology and transplant cases.

Research Contributions
Although clinical exposure was my primary goal, I was also engaged in research. I co-authored a review of therapies in autoimmune hepatitis and contributed to a review on PSC, which is currently in progress. I co-authored six abstracts submitted to EASL, addressing a range of important topics:

  • Third-line therapy in autoimmune hepatitis.
  • Post-transplant outcomes in PSC and IBD.
  • Frailty in steatotic liver disease on the transplant waiting list.
  • Ammonia as a prognostic tool in liver disease.

In addition to these abstracts. These research opportunities deepened my academic expertise and allowed me to collaborate with leaders in hepatology.

Educational Contributions
Education was another meaningful component of my fellowship. Highlights include:

  • Teaching liver pharmacists about MDR3 deficiency, bridging the gap between pharmacology and clinical hepatology.
  • Presenting three M&M rounds, including a particularly challenging case involving a postpartum death, which emphasized the importance of reflection and multidisciplinary learning.

Looking Ahead

My time as a CASL-CLF fellow at KCH has been transformative. From acting as a consultant to managing transplant cases and contributing to academic advancements, this year has equipped me with the skills, knowledge, and confidence to excel as a hepatologist. I look forward to bringing these experiences back to Canada and contributing meaningfully to the hepatology community. I am grateful that CASL-CLF allowed me the opportunity to do so.

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