{"id":4803,"date":"2025-06-18T20:08:21","date_gmt":"2025-06-18T20:08:21","guid":{"rendered":"https:\/\/hepatology.ca\/?p=4803"},"modified":"2025-10-10T15:44:58","modified_gmt":"2025-10-10T15:44:58","slug":"the-management-of-chronic-hepatitis-b-2025-guidelines-update","status":"publish","type":"post","link":"https:\/\/hepatology.ca\/fr\/2025\/06\/18\/the-management-of-chronic-hepatitis-b-2025-guidelines-update\/","title":{"rendered":"Prise en charge de l&#039;h\u00e9patite B chronique\u00a0: mise \u00e0 jour des lignes directrices 2025 sur le VHB"},"content":{"rendered":"<p>L&#039;Association canadienne pour l&#039;\u00e9tude du foie (ACEF) et la <a href=\"https:\/\/ammi.ca\/en\/\">Association canadienne de microbiologie m\u00e9dicale et d&#039;infectiologie (AMMI)<\/a> ont publi\u00e9 leurs tr\u00e8s attendues lignes directrices 2025 pour la prise en charge de l&#039;h\u00e9patite B chronique (VHB). Ces lignes directrices actualis\u00e9es refl\u00e8tent les derni\u00e8res avanc\u00e9es de la recherche et de la pratique clinique, visant \u00e0 am\u00e9liorer les soins et les r\u00e9sultats pour les patients.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Principales mises \u00e0 jour et recommandations<\/h3>\n\n\n\n<p><strong>1. D\u00e9pistage et diagnostic am\u00e9lior\u00e9s :<\/strong>&nbsp;Les lignes directrices de 2025 soulignent l&#039;importance d&#039;une d\u00e9tection pr\u00e9coce gr\u00e2ce \u00e0 des protocoles de d\u00e9pistage renforc\u00e9s. Elles recommandent un d\u00e9pistage syst\u00e9matique pour les populations \u00e0 haut risque, notamment les immigrants provenant de r\u00e9gions end\u00e9miques, les personnes ayant des ant\u00e9c\u00e9dents de consommation de drogues par voie intraveineuse et les personnes vivant avec le VIH.<\/p>\n\n\n\n<p><strong>2. Algorithmes de traitement mis \u00e0 jour\u00a0:<\/strong>&nbsp;Les nouvelles recommandations introduisent des algorithmes de traitement actualis\u00e9s int\u00e9grant les derni\u00e8res th\u00e9rapies antivirales. Ces algorithmes sont con\u00e7us pour proposer des plans de traitement personnalis\u00e9s en fonction du stade de la maladie, de la charge virale et de la fonction h\u00e9patique du patient.<\/p>\n\n\n\n<p><strong>3. Mettre l\u2019accent sur la surveillance \u00e0 long terme :<\/strong>&nbsp;Une surveillance \u00e0 long terme est essentielle pour une prise en charge efficace de l&#039;h\u00e9patite B chronique. Les recommandations pr\u00e9conisent un suivi r\u00e9gulier avec des tests de la fonction h\u00e9patique, des \u00e9valuations de la charge virale et des examens d&#039;imagerie afin de d\u00e9tecter toute progression de la maladie h\u00e9patique ou le d\u00e9veloppement d&#039;un carcinome h\u00e9patocellulaire (CHC).<\/p>\n\n\n\n<p><strong>4. Int\u00e9gration de nouveaux agents antiviraux :<\/strong>&nbsp;La mise \u00e0 jour 2025 inclut des recommandations pour l&#039;utilisation de nouveaux agents antiviraux qui se sont r\u00e9v\u00e9l\u00e9s prometteurs lors d&#039;essais cliniques. Ces agents offrent des profils d&#039;efficacit\u00e9 et de s\u00e9curit\u00e9 am\u00e9lior\u00e9s, offrant davantage d&#039;options aux patients qui pourraient ne pas r\u00e9pondre aux traitements traditionnels.<\/p>\n\n\n\n<p><strong>5. S\u2019adresser aux populations particuli\u00e8res :<\/strong>&nbsp;Une attention particuli\u00e8re est accord\u00e9e \u00e0 la gestion du VHB chronique chez les femmes enceintes, les enfants et les personnes atteintes de co-infections telles que le VIH ou l\u2019h\u00e9patite C. Les lignes directrices fournissent des recommandations personnalis\u00e9es pour garantir que ces populations re\u00e7oivent des soins appropri\u00e9s.<\/p>\n\n\n\n<p><strong>6. Sant\u00e9 publique et pr\u00e9vention :<\/strong>&nbsp;Les lignes directrices soulignent l\u2019importance de la vaccination et des initiatives de sant\u00e9 publique pour pr\u00e9venir la propagation de l\u2019h\u00e9patite B. Elles pr\u00e9conisent l\u2019intensification des campagnes de sensibilisation et des programmes de vaccination, en particulier dans les communaut\u00e9s \u00e0 haut risque.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">S\u00e9rie de webinaires \u00e9ducatifs sur la LCAP\u00a0: Introduction aux lignes directrices mises \u00e0 jour sur le VHB 2025 (9 octobre 2025)<\/h3>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Introduction aux directives mises \u00e0 jour sur le VHB 2025\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/i_l42gYqGw8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusion<\/h3>\n\n\n\n<p>Les lignes directrices 2025 de l&#039;ACF et de l&#039;AMMI repr\u00e9sentent une avanc\u00e9e significative dans la prise en charge de l&#039;h\u00e9patite B chronique. En int\u00e9grant les recherches et les pratiques cliniques les plus r\u00e9centes, ces lignes directrices visent \u00e0 am\u00e9liorer les r\u00e9sultats pour les patients et \u00e0 r\u00e9duire le fardeau de l&#039;h\u00e9patite B chronique au Canada. Les professionnels de la sant\u00e9 sont encourag\u00e9s \u00e0 se familiariser avec ces mises \u00e0 jour et \u00e0 les int\u00e9grer \u00e0 leur pratique afin d&#039;assurer les meilleurs soins possibles \u00e0 leurs patients.<\/p>\n\n\n\n<p><strong>Auteurs<\/strong>:&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con1\">Pr\u00e9sident du comit\u00e9 des lignes directrices sur la pratique clinique<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con2\">Carla Osiowy, Ph. D.<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con3\">Membres du panel<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con4\">Dr Fernando Alvarez<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con5\">Carla S. Coffin, MD, MSc<\/a>&nbsp;<a href=\"mailto:Scott.Fung@uhn.ca?cc=cscoffin@ucalgary.ca\">Scott.Fung@uhn.ca<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con6\">Dr Curtis L. Cooper<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con7\">Dr Scott K. Fung<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con8\">Hin Hin Ko<\/a>,&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con9\">S\u00e9bastien Poulin, M.D., M.Sc.<\/a>, et&nbsp;<a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#con10\">Jennifer van Gennip, BSc<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/utppublishing.com\/doi\/10.3138\/canlivj-2025-0012-e#tab-contributors\">Informations et affiliations des auteurs<\/a><\/p>\n\n\n\n<p>Pour des informations plus d\u00e9taill\u00e9es, les professionnels de la sant\u00e9 peuvent acc\u00e9der aux lignes directrices compl\u00e8tes sur le Journal canadien du foie \u2013 Volume 8, num\u00e9ro 2 \u2013 <a href=\"https:\/\/doi.org\/10.3138\/canlivj-2025-0012-e\">https:\/\/doi.org\/10.3138\/canlivj-2025-0012-e<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/utppublishing.com\/personalize\/addFavoritePublication?doi=10.3138%2Fcanlivj-2025-0012-e\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>The Canadian Association for the Study of the Liver (CASL) and the Association of Medical Microbiology and Infectious Disease Canada [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ngg_post_thumbnail":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4803","post","type-post","status-publish","format-standard","hentry","category-casl-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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